Pentobarbital will decrease the level or effect of prednisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital will decrease the level or effect of vincristine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. When barbiturates like Nembutal are abused, they are not usually the primary drug of abuse. Like https://brightbookmarks.com/story20506585/indicatori-sulla-pentobarbital-si-deve-sapere