, ritonavir) or discontinuation of the cytochrome P450 3A4 inducer such as rifampin, carbamazepine, and phenytoin, might cause an increase in codeine plasma concentrations with subsequently bigger metabolism by cytochrome P450 2D6, causing better morphine degrees, which could improve or extend adverse reactions and may cause perhaps fatal respiratory depression. https://emilianoycbyv.pointblog.net/5-essential-elements-for-akorn-codeine-75036505