If a parent from the proband is known to provide the pathogenic variant recognized in the proband, the chance for the sibs of inheriting the pathogenic variant is 50%. Thanks to minimized penetrance, sibs who inherit the pathogenic variant might or might not acquire aHUS (see Penetrance). The family heritage https://gregorydariy.blogpayz.com/34163634/the-fact-about-air-handling-units-ahus-that-no-one-is-suggesting